Normothermic Regional Perfusion
This activity consists of a recorded presentation from the "Essentials of Oncology, Solid Organ and Blood/Marrow Transplant Management for the Health Care Team" conference held in Scottsdale, Ariz., March 14–15, 2022.
Normothermic regional perfusion (NRP) plays a large role in improving graft survival and posttransplant outcomes through restoring continuous perfusion and reversing warm ischemic injury to organs donated after circulatory death. The utility of NRP has continued to expand, and data describing the use of NRP-heart-transplantation protocols such as cardiopulmonary bypass, thoraco-abdominal, or modified extracorporeal membrane oxygenation (ECMO) circuit have demonstrated effective and successful outcomes. This presentation will discuss the opportunities presented by NRP to increase the availability of donor organs and allow for extended patient survival time until transplant. The principles of NRP, effects on graft survival, potential complications, and ethical and legal concerns will be reviewed.
This activity is provided by OptumHealth Education.
There was no commercial support for this activity.
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This activity is designed to meet the educational needs of case managers, nurses, pharmacists, pharmacy technicians, physicians, psychologists, social workers, dietitians, and other health care professionals who are interested in transplantation and the use of normothermic regional perfusion.
At the end of this educational activity, participants should be able to:
- Review the status of NRP utilization in donation after circulatory death (DCD) organ transplantation, including principles, techniques, and effects on graft quality and clinical outcomes.
- Discuss current data regarding heart-transplantation techniques using NRP/DCD.
- Identify possible complications, as well as ethical and legal concerns, associated with NRP/DCD.
- Describe the potential ability of NRP to increase the availability of donor organs for transplantation.
Victor Pretorius, MBChB
Surgical Director, Cardiac Transplant and Mechanical Circulatory Support
UC San Diego Health
San Diego, CA
About the presenter
Dr. Victor Pretorius is a board-certified cardiothoracic surgeon who specializes in lead management. Pacemakers and implantable cardioverter-defibrillators (ICDs) deliver energy to the heart through thin, flexible wires called leads. When these leads are not working properly — because of infection, damage or surrounding scar tissue — they need to be removed. Dr. Pretorius performs a minimally invasive procedure called laser lead extraction to cut through scar tissue surrounding the lead, allowing it to be easily removed. Dr. Pretorius is surgical director of UC San Diego Health’s Heart Transplant Program, which provides comprehensive and compassionate care from a multidisciplinary team of experts in the fields of advanced heart failure, cardiac surgery and cardiac transplantation. As an associate professor in the Department of Surgery at UC San Diego School of Medicine, Dr. Pretorius publishes papers about the procedure and presents his findings at conferences around the world. He completed a fellowship in pulmonary thromboendarterectomy at UC San Diego School of Medicine and a residency in cardiac surgery at University of Alberta, Edmonton, Canada. He earned his medical degree (MBChB) from the University of Pretoria School of Medicine in his native South Africa. Dr. Pretorius is a Fellow of the Royal College of Surgeons of Canada (FRCSC). FRCSC is equivalent to board certification in the U.S.
Elizabeth Albert, MD
Clinical Activity Manager
Eden Prairie, MN
Matthew Cooper, MD
President, UNOS Board of Directors;
Director, Kidney and Pancreas Transplantation
Medstar Georgetown Transplant Institute;
Professor of Surgery
Georgetown University School of Medicine
Rebecca Gleason, RN, CCM
Eden Prairie, MN
Alan N. Langnas, DO, FACS
Professor of Surgery
Director, Center of Transplantation
Chief, Section of Transplantation,
Department of Surgery
University of Nebraska Medical Center;
Director of Liver Transplantation
C. Fred LeMaistre, MD
Senior Vice President
Senior Vice President, Market Operations
Tina Rydland, PharmD
Disclosures of relevant financial relationships
In accordance with the Accreditation Council for Continuing Medical Education's (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, OptumHealth Education (OHE) requires all those in control of educational content to disclose their financial relationships with ineligible companies within the prior 24 months. Ineligible companies are defined by the ACCME as companies whose primary business is producing, marketing, selling, re-selling, or distributing health care products used by or on patients. Individuals must disclose all financial relationships, regardless of the amount, with ineligible companies and regardless of their view of the relevance of the relationship to the education. OHE ensures that the content is independent of commercial bias.
The activity faculty and planners have no financial relationships to disclose.
Method for calculating CE credit
CE credit was calculated by the complexity of content.
In support of improving patient care, OptumHealth Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the health care team.
Credit designation statements
This activity was planned by and for the health care team, and learners will receive 0.75 Interprofessional Continuing Education (IPCE) credits for learning and change.
The participant will be awarded up to 0.75 contact hour(s) of credit for attendance and completion of supplemental materials.
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts credit from organizations accredited by the ACCME and ANCC.
This activity is approved for 0.75 contact hour(s) ([0.075] CEU) in states that recognize ACPE.
Attending the full program will earn 0.75 contact hour(s).
Unique Activity Number(s): JA0007123-0000-22-142-H01-P/T
OptumHealth Education designates this enduring activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American Academy of Physician Assistants (AAPA) accepts credit from organizations accredited by the ACCME.
The Commission for Case Manager Certification has approved this program for a maximum of 0.75 clock hour(s) for Certified Case Managers (CCM).
Completion of this RD/DTR profession-specific or IPCE activity awards CPEUs (One IPCE credit=One CPEU).
If the activity is dietetics-related but not targeted to RDs or DTRs, CPEUs may be claimed which are commensurate with participation in contact hours (One 60 minute hour=1 CPEU).
RD's and DTRs are to select activity type 102 in their Activity Log. Performance indicator selection is at the learner's discretion.
Psychologists and social workers
Participants must have attended the entire Web-based activity and completed an evaluation to receive a certificate. Partial credit is not available.
OptumHealth Education is approved by the American Psychological Association (APA) to offer continuing education for psychologists. OptumHealth Education maintains responsibility for this program. 0.75 CE hour.
As a Jointly Accredited Organization, OptumHealth Education is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. OptumHealth Education maintains responsibility for this course. Social workers completing this course receive 0.75 enduring continuing education credit.
A certificate of attendance will be provided to learners upon completion of activity requirements, enabling participants to register with licensing boards or associations that have not been preapproved for credits. To apply for credit types not listed above, participants should use the procedure established by the specific organization with which they wish to obtain credit.
- 0.75 ACPE - Pharmacists
- 0.75 ACPE - Pharmacy Technicians
- 0.75 AMA - Physicians
- 0.75 ANCC - Nurses
- 0.75 APA - Psychologists
- 0.75 Attendance - General Attendance
- 0.75 CCMC - General - Case Managers
- 0.75 CDR - Dietitians
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