Incompatible Kidney Transplantation: National Strategies and Outcomes
The considerable shortage of organ donors and increasing number of patients with end-stage renal disease has led to an extended waiting time for potential renal-allograft recipients. ABO-incompatible kidney transplantation was previously considered to be an absolute contraindication for patients with end-stage kidney disease (ESKD) due to hyperacute rejection related to blood-type barrier. With the need to expand the donor pool and minimize shortage of kidneys for transplantation, ABO-incompatible kidney transplantation (ABOi KT) was introduced. Another way to offset the extended waiting time and shortage of organ donors is Kidney Paired Donation (KPD) as a transplant option for candidates who have a living donor who is medically able, but cannot donate a kidney to their intended candidate because the two individuals are physiologically incompatible. This activity will discuss the various approaches to matching and allocation in KPD and identify strategies for transplantation across blood barriers in ABO-incompatible kidney transplantation.
At the end of this educational activity, participants should be able to
- Define immunotherapy and distinguish it from chemotherapy
- Discuss the various approaches to matching and allocation in KPD. Identify strategies for kidney transplantations across blood barriers
Dorry Segev, MD, PhD
Marjory K. and Thomas Pozefsky Professor of Surgery and Epidemiology
Director, Epidemiology Research Group in Organ Transplantation
Associate Vice Chair, Department of Surgery
Johns Hopkins University
Disclosures of Relevant Financial Relationships
In accordance with the ACCME Standards for Commercial SupportSM, OptumHealth Education requires all those involved in the development of activity content to disclose their relevant financial relationships. An individual has a relevant financial relationship if such person (or their spouse/partner) has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the activity content over which the individual has control.
OptumHealth Education ensures that the content is independent of commercial bias.
Dr Segev has indicated that he has no relevant financial relationships.
Michael Abecassis, MD, MBA
Sarah Chart, RN
Eden Prairie, MN
Rebecca Gleason, RN, CCM
Eden Prairie, MN
Dixon B. Kaufman, MD, PhD, FACS
University of Wisconsin School of Medicine and Public Health
C. Fred LeMaistre, MD
Tina Rydland, PharmD
Crystal Clear Rx
V. Silverstein, MD
Eagle Creek Medical Communications
Activity Planner Disclosures
Drs Abecassis, Kaufman, LeMaistre, Rydland and Silverstein have indicated that they have no relevant financial relationships.
Ms Chart and Ms Gleason have indicated that they are employees of and own stock in UnitedHealth Group.
To ensure fair balance and avoid bias, the content for this activity has been reviewed by an independent medical expert with no relevant financial relationships.
Method of Participation
There are no fees for participating in or receiving credit for this activity.
For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.
Participants will receive a certificate upon successful completion of the activity, which includes the following:
- Completing the entire activity
- Completing the Pre- and Post-Activity Assessments, Activity Evaluation, and Application for Certificate of Credit forms
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Method for Calculating CE Credit
CE credit was calculated by the complexity of content.
In support of improving patient care, OptumHealth Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the health care team.
Credit Designation Statements
OptumHealth Education designates this enduring activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American Academy of Physician Assistants (AAPA) accepts credit from organizations accredited by the ACCME.
The participant will be awarded up to 0.75 contact hour(s) of credit for attendance and completion of supplemental materials.
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts credit from organizations accredited by the ACCME and ANCC.
The Commission for Case Manager Certification has approved this program for a maximum of 0.75 clock hour(s) for Certified Case Managers (CCM). (Please reference the 25th Annual National Conference when contacting CCMC to claim credit for this activity.)
This activity is approved for 0.75 contact hour(s) ([0.075] CEU) in states that recognize ACPE.
Attending the full program will earn 0.75 contact hour(s).
Unique Activity Number(s): 0860-0000-16-020-H01P/0860-0000-16-020-H01T
A certificate of attendance will be provided to learners upon completion of activity requirements, enabling participants to register with licensing boards or associations that have not been pre-approved for credits. To apply for credit types not listed above, participants should use the procedure established by the specific organization to which you wish you apply credit.
This activity is provided by OptumHealth Education.
No commercial support was received for this activity.
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This activity is designed to meet the educational needs of case managers, nurses, pharmacists, pharmacy technicians, physicians and other health care professionals who are interested in kidney transplantation.
This activity consists of recorded presentations from the "25th Annual National Conference" held in Minneapolis, MN on October 5–7, 2016.
- 0.75 ACPE - Pharmacist
- 0.75 ACPE - Pharmacy Technician
- 0.75 AMA
- 0.75 ANCC
- 0.75 Attendance
- 0.75 CCMC - General