A Cure for Diabetes? Innovations from Pancreas to Islet-Cell to Beta-Cell Transplantation
The discovery of insulin transformed type 1 diabetes from a fatal disease to a manageable condition, but it remains a very serious chronic illness. Islet-cell or pancreatic transplantation can, in principle, cure type 1 diabetes, but lifelong immunosuppressive therapy is required and the lack of donor pancreas tissue has led to attempts to find alternative treatment of type 1 diabetes. This session will discuss the Clinical Islet Transplantation Consortium (CIT) study and the advances in pancreatic-islet-cell transplant and kidney/pancreas transplant. It will also explore the utility of stem-cell-derived beta cells for future treatment of diabetes and the challenges faced in developing beta-cell replacement therapies.
At the end of this educational activity, participants should be able to
- Provide a brief overview of the history of pancreas transplantation for the treatment of type 1 diabetes
- Identify advances in the technical and immunologic aspects of islet transplantation that resulted in achieving long-lasting insulin independence
- Analyze the results of the Clinical Islet Transplantation Consortium (CIT) study through the National Institutes of Health (NIH) for allogeneic islet-cell transplantation for the treatment of diabetes
- Discuss the utility of stem-cell-derived beta cells for future treatment of diabetes and the challenges faced in developing beta-cell-replacement therapies
- Describe factors health care providers should consider when referring patients for pancreatic islet cell transplant and kidney/pancreas transplants
Dixon B. Kaufman, MD, PhD, FACS
Ray D. Owens Professor of Surgery
Chief, Division of Transplantation
University of Wisconsin School of Medicine and Public Health;
Disclosures of Relevant Financial Relationships
In accordance with the ACCME Standards for Commercial SupportSM, OptumHealth Education requires all those involved in the development of activity content to disclose their relevant financial relationships. An individual has a relevant financial relationship if such person (or their spouse/partner) has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the activity content over which the individual has control.
OptumHealth Education ensures that the content is independent of commercial bias.
Dr Kaufman has indicated that he has no relevant financial relationships.
Michael Abecassis, MD, MBA
Sarah Chart, RN
Eden Prairie, MN
Rebecca Gleason, RN, CCM
Eden Prairie, MN
Dixon B. Kaufman, MD, PhD, FACS
University of Wisconsin School of Medicine and Public Health
C. Fred LeMaistre, MD
Tina Rydland, PharmD
Crystal Clear Rx
V. Silverstein, MD
Eagle Creek Medical Communications
Activity Planner Disclosures
Drs Abecassis, Kaufman, LeMaistre, Rydland and Silverstein have indicated that they have no relevant financial relationships.
Ms Chart and Ms Gleason have indicated that they are employees of and own stock in UnitedHealth Group.
To ensure fair balance and avoid bias, the content for this activity has been reviewed by an independent medical expert with no relevant financial relationships.
Method of Participation
There are no fees for participating in or receiving credit for this activity.
For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.
Participants will receive a certificate upon successful completion of the activity, which includes the following:
- Completing the entire activity
- Completing the Pre- and Post-Activity Assessments, Activity Evaluation, and Application for Certificate of Credit forms
You must be logged into your account to participate in this activity. Get started by clicking “Begin” and viewing the “CE Info”; then follow the prompts at the bottom of the screen. At the end of the activity, you will be able to view, save, or print your certificate of participation. The Area of Practice you indicated in your profile corresponds with your certificate type. A complete listing of all of your activities can be found under “My Account”, “My Activities.”
Method for Calculating CE Credit
CE credit was calculated by the complexity of content.
In support of improving patient care, OptumHealth Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the health care team.
Credit Designation Statements
OptumHealth Education designates this enduring activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American Academy of Physician Assistants (AAPA) accepts credit from organizations accredited by the ACCME.
The participant will be awarded up to 0.75 contact hour(s) of credit for attendance and completion of supplemental materials.
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts credit from organizations accredited by the ACCME and ANCC.
The Commission for Case Manager Certification has approved this program for a maximum of 0.75 clock hour(s) for Certified Case Managers (CCM). (Please reference the 25th Annual National Conference when contacting CCMC to claim credit for this activity.)
This activity is approved for 0.75 contact hour(s) ([0.075] CEU) in states that recognize ACPE.
Attending the full program will earn 0.75 contact hour(s).
Unique Activity Number(s): 0860-0000-16-010-H01P/0860-0000-16-010-H01T
A certificate of attendance will be provided to learners upon completion of activity requirements, enabling participants to register with licensing boards or associations that have not been pre-approved for credits. To apply for credit types not listed above, participants should use the procedure established by the specific organization to which you wish you apply credit.
This activity is provided by OptumHealth Education.
No commercial support was received for this activity.
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This activity is designed to meet the educational needs of case managers, nurses, pharmacists, pharmacy technicians, physicians and other health care professionals who are interested in diabetes.
This activity consists of recorded presentations from the "25th Annual National Conference" held in Minneapolis, MN on October 5–7, 2016.
- 0.75 ACPE - Pharmacist
- 0.75 ACPE - Pharmacy Technician
- 0.75 AMA
- 0.75 ANCC
- 0.75 Attendance
- 0.75 CCMC - General