Transplantation: Essentials of Solid Organ and Blood/Marrow Transplant Management for the Health Care Team
TUESDAY, APRIL 12, 2016 — SOLID ORGAN TRANSPLANTION — Attending the full daily program will earn 6.5 contact hours (.65 CEUs). Unique Activity Number 0860-0000-15-048-L01-P
Thoracic Transplantation 101: Evaluation, Hospitalization, Posttransplant Care and Complications, Michael Petty, PhD, RN, CCNS, ACNS-BC, University of Minnesota Health
Heart and lung transplantation have revolutionized therapy for end-stage thoracic disease in the last decade. There are important factors that need to be taken into consideration to optimize outcomes for this patient population. The appropriate timing for referral to a transplant program is based on the patient’s functional status and life expectancy. With thoracic transplantation, there is a significant risk of perioperative morbidity and mortality; therefore, each patient needs to be evaluated individually, with consideration for absolute and relative contraindications. This session will discuss the advantages of a comprehensive multidisciplinary approach to managing thoracic transplant recipients. An overview of the criteria and evaluation process for thoracic transplantation, hospital course, and pre- and posttransplant management strategies will be presented along with how a team can work together to achieve optimal patient outcomes.
Left Ventricular Assist Devices (LVADs): Optimal Management to Reduce Morbidity and Mortality in Heart Failure Patients, Michael Petty, PhD, RN, CCNS, ACNS-BC, University of Minnesota Health
An LVAD is a mechanical pump that is used to support heart function and blood flow in people who have weakened hearts. This treatment option is for certain patients with end-stage heart failure and can be used either as a bridge to transplant until a donor heart becomes available for transplant or as destination therapy as an alternative to heart transplant. This session will review (1) candidate selection; (2) management strategies to reduce morbidity and mortality in heart failure patients supported with LVADs; (3) outpatient strategies to optimize device performance and heart failure management; and (4) important device complications that warrant close outpatient monitoring.
Abdominal Transplantation 101: Treatable Diseases, Evaluation, Hospitalization and Posttransplant Care, George E. Loss, Jr., MD, PhD, FACS, Ochsner Medical Center
Organ transplantation has overcome major technical limitations to become the success it is today. The breakthroughs include developing techniques for vascular anastomoses and managing the immune response.The outcomes of organ transplantation continue to improve with advancements in the evaluation and selection process, as well as the peri- and postoperative management of these patients. This session will include an overview of abdominal organ transplantation, organ-specific outcomes, the use of deceased versus living donors, the role of immunosuppression therapy, and short- and long-term complications associated with these surgeries — such as infection, disease recurrence, and acute and chronic rejection.
An Overview of Pharmaceuticals Utilized in Organ Transplantation, Andrew Freeman, PharmD, BCPS, Ochsner Medical Center
The success of solid organ transplantation rests heavily on the major advances in immunosuppressive therapy. With the introduction of improved immunosuppressive agents to prevent graft rejection, as well as antimicrobials and antifungal agents to decrease the risk of opportunistic infection, successful organ transplantation has become the standard. The use of risk education and management strategies (REMS) are becoming increasingly common in organ transplantation, and studies suggest that health care providers must be aware of these strategies to improve patient education and reduce pharmaceutical risk. This session will discuss immunosuppressive agents used in organ transplantation and the major adverse effects for each agent.
Organ Procurement: Strategies to Close the Gap Between the Supply and Demand for Organs, Stuart C. Sweet, MD, PhD, St. Louis Children's Hospital
Organ transplantation has been limited by the shortage of donor organs, resulting in a significant imbalance between organ availability and the need for organ transplantation services. Despite advances in medicine and technology, as well as increased awareness of organ donation and transplantation, the gap between supply and demand continues to widen. The U.S. Organ Procurement and Transplantation Network (OPTN) helps ensure the success and efficiency of the U.S. organ transplantation system. This session will review the goals of the OPTN and discuss strategies to increase organ donation that will close the gap between suppy and demand.
Immune Tolerance in Kidney and Liver Transplantation: What’s New? R. Mark Ghobrial, MD, PhD, FACS, FRCS (Ed), Methodist J.C. Walter Jr. Transplant Center
One of the biggest battles associated with organ transplantation is the management of side effects resulting from lifelong use of immunosuppression. The toxicity of chronic immunosuppressive agents has prompted investigators to pursue approaches to induce immune tolerance. The goal is to wean transplant recipients off immunosuppressive agents while keeping graft function stable, in the hope of making it possible for patients to live without the need for immunosuppressive drugs. This session will offer information about novel agents that produce immune tolerance, including chimerism and donor-specific tolerance in kidney and liver transplant recipients.
Congenital Heart Disease (CHD): Incidence, Diagnosis, Complications and Management, Wayne J. Franklin, MD, FACC, Texas Children's Hospital, Baylor St. Luke's Medical Center
According to the Centers for Disease Control (CDC), 1 percent of babies born in the United States have congenital heart defects. They range from simple defects with no symptoms to complex defects with severe, life-threatening symptoms. The diagnosis and treatment of CHD has greatly improved over the past few decades and, as a result, almost all children who have complex heart defects survive to adulthood and can live active, productive lives. With this increased longevity, children with CHD grow out of needing pediatric care, and health care providers who take care of adults are now managing this patient population. Studies suggest that this transition may be challenging, and health care providers do not always know the best way to smoothly transition care for these patients This session will review the types, signs and symptoms, diagnoses, and treatments for complex CHD. It will also review the impact congenital heart defects have on quality of life and self-efficacy in children and adults with this disease and the challenges that children face as they transition from pediatric to adult care.
Chronic Kidney Disease (CKD): Overcoming Barriers to Patient Care and to Successful Implementation of Clinical Guidelines, Cybele Ghossein, MD, Northwestern Medicine
The CDC reports that over 20 million adults in the United States suffer from CKD. Despite the presence of clinical guidelines, including those created by the National Kidney Foundation, studies suggest that there are numerous barriers to implementation, such as patient-, provider- and system-associated barriers. This session will review the latest treatment guidelines for CKD, outline a model to identify at-risk patients and discuss how to effectively overcome barriers to care. It will also review the importance of optimal timing for referral of CKD patients to a nephrologist.
- 6.50 ACPE - Pharmacists