Understanding Myeloma Genetics May Lead to Individualized Therapies
The treatment of multiple myeloma (MM) is complex because of rapid advances in stem-cell transplantation, medications, and better supportive care, all of which have led to improved patient survival. Overall, the care of patients should focus on treatment of the disease process and any associated complications. The diagnostic criteria for and management of MM in the updated 2016 NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) broadens the population of patients eligible for therapy by expanding the active myeloma category and also integrating novel therapies at all stages of the disease. Dr. Van Ness will review current and new therapeutic approaches for the treatment of MM and will address the challenges that exist in the treatment of this disease. He will also identify genetic approaches to characterize variations in tumor progression and will address how to determine the best therapy to maximize effectiveness and response for each individual patient. Ms. Ahlstrom will discuss how Myeloma Crowd believes that educated and involved patients can drive better outcomes for themselves, be part of the solution to better care, and accelerate the discovery of a cure for their own disease.
At the end of this educational activity, participants should be able to
- Describe current therapeutic approaches in the treatment of MM
- List some of the challenges that exist in the treatment of MM
- Identify genetic approaches to characterize variations in tumor progression and response
- Discuss ways of determining which therapies work best for each individual
- Describe the role of using genetics and bioinformatic tools to identify individual tumor signatures of response or resistance
- Understand the treatment and management of an MM diagnosis from a patient’s perspective
- State the vital role education plays in empowering patients to participate in their treatment pathway and optimize their care
- Explain the potential impact of participating in a clinical trial to enable patients with MM to receive the most current treatments while assisting in research for a cure
- Recognize the importance of receiving treatment from a myeloma specialist versus a general oncologist
Founder, Myeloma Crowd and CrowdCare Foundation
Brian Van Ness, PhD
Department of Genetics, Cell Biology and Development
College of Biological Sciences
University of Minnesota Cancer Center
Disclosures of Relevant Financial Relationships
In accordance with the ACCME Standards for Commercial SupportSM, OptumHealth Education requires all those involved in the development of activity content to disclose their relevant financial relationships. An individual has a relevant financial relationship if such person (or their spouse/partner) has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the activity content over which the individual has control.
OptumHealth Education ensures that the content is independent of commercial bias.
Ms Ahlstrom has disclosed the following: Bristol-Myers Squibb, Takeda Oncology (Consultant)
Dr Van Ness has disclosed the following: OneOme (Consultant)
Michael Abecassis, MD, MBA
Sarah Chart, RN
Eden Prairie, MN
Rebecca Gleason, RN, CCM
Eden Prairie, MN
Dixon B. Kaufman, MD, PhD, FACS
University of Wisconsin School of Medicine and Public Health
C. Fred LeMaistre, MD
Tina Rydland, PharmD
Crystal Clear Rx
V. Silverstein, MD
Eagle Creek Medical Communications
Activity Planner Disclosures
Drs Abecassis, Kaufman, LeMaistre, Rydland and Silverstein have indicated that they have no relevant financial relationships.
Ms Chart and Ms Gleason have indicated that they are employees of and own stock in UnitedHealth Group.
To ensure fair balance and avoid bias, the content for this activity has been reviewed by an independent medical expert with no relevant financial relationships.
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- Completing the entire activity
- Completing the Pre- and Post-Activity Assessments, Activity Evaluation, and Application for Certificate of Credit forms
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CE credit was calculated by the complexity of content.
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Credit Designation Statements
OptumHealth Education designates this enduring activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American Academy of Physician Assistants (AAPA) accepts credit from organizations accredited by the ACCME.
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This activity is approved for 0.75 contact hour(s) ([0.075] CEU) in states that recognize ACPE.
Attending the full program will earn 0.75 contact hour(s).
Unique Activity Number(s): 0860-0000-16-017-H01P/0860-0000-16-017-H01T
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This activity is designed to meet the educational needs of case managers, nurses, pharmacists, pharmacy technicians, physicians and other health care professionals who are interested in myeloma.
This activity consists of recorded presentations from the "25th Annual National Conference" held in Minneapolis, MN on October 5–7, 2016.
- 0.75 ACPE - Pharmacists
- 0.75 ACPE - Pharmacy Technicians
- 0.75 AMA - Physicians
- 0.75 ANCC - Nurses
- 0.75 Attendance - General Attendance
- 0.75 CCMC - General - Case Managers