Printable Schedule-at-a-Glance (Updated: 3/12/15)Register

Monday, April 13
Tuesday, April 14

MONDAY, APRIL 13, 2015Up to 6.75 continuing education credits available.—ACPE UAN 0860-0000-15-026-L01-P

7:00 a.m.

Registration and Continental Breakfast

8:00 a.m.

Welcome and Opening Remarks


8:15 a.m.

An Overview of Blood/Marrow Transplantation, C. Fred LeMaistre, MD, Sarah Cannon Cancer Services 

Blood and marrow transplantation (BMT) is the accepted therapy of choice for a variety of malignant and nonmalignant diseases in children and adults. Improvements in transplantation techniques, center experience, and donor availability have enabled BMT to reach an ever-growing number of patients worldwide.

This session will describe the different types of BMT and sources of stem cells and will explain the engraftment process, graft-vs-host disease, graft-vs-tumor, and graft-vs-leukemia effect. We will also provide an understanding of remission and chemo-sensitive disease; immunosuppression therapy and its role in blood/marrow transplantation; the significance of clinical trials; and the importance of a multidisciplinary team approach to achieve optimal outcomes in patients undergoing BMT.

Learning Objectives:

  1. Define and explain the different types of blood/marrow transplants and the various sources of stem cells.
  2. Explain the mechanisms of rejection, infection, acute and chronic graft-vs-host disease, and other posttransplant complications.
  3. Provide an explanation of immunosuppression therapy and its role in blood/marrow transplantation.
  4. State the significance of clinical trials in BMT.
  5. Discuss the importance of multidisciplinary team approach to maximize patient outcomes.

9:45 a.m.


10:00 a.m.

National Marrow Donor Program: Resource for Unrelated Donor Stem Cell Transplantation, Jeffrey W. Chell, MD, National Marrow Donor Program

Over the past 25 years Be The Match®, operated by the National Marrow Donor Program® (NMDP), has managed the largest and most diverse marrow registry in the world. Using innovative science and technology, the NMDP works with patients and their doctors to help find the best match with a donor or cord blood unit for a life-saving marrow or blood cell transplant. This session will provide a global overview of the role of the NMDP as it relates to allogeneic transplantation and the use of unrelated blood/marrow transplant donors.

Learning Objectives:

  1. Define the role of the National Marrow Donor Program (NMDP) in unrelated donor stem cell transplantation.

10:45 a.m.

BMT in Adults: Indications, Prognostic Factors and Posttransplant Management, Michael R. Bishop, MD, University of Chicago Medicine

BMT is at the forefront of one of the most fascinating and revolutionary areas of medicine today. A wide range of diseases are treated with transplantation including acute and chronic forms of leukemia, lymphoma, myeloproliferative disorders, myeloma, inherited metabolic disorders, and many more. This session will discuss the indications and diseases treatable with BMT in the adult population. The prognostic factors that can predict outcomes for these patients, along with posttransplant management strategies will also be reviewed.

Learning Objectives:

  1. State the indications for BMT in adults.
  2. List the types of diseases that are indicated for transplantation in adults.
  3. Discuss the prognostic factors that can predict outcomes of BMT.
  4. Identify posttransplant management strategies for BMT recipients to maximize patient outcomes.

11:45 a.m.

Luncheon Presentation: An Overview of Optum (optional)

1:15 p.m.

Management of Physiological Complications Associated With Pediatric BMT Patients, Kristen L. Beebe, MS, PA-C, Phoenix Children's Hospital and Mayo Clinic Arizona

BMT has become a common treatment practice in many childhood diseases and continues to increase as new indications for transplant emerge. Survivors often have long-term organ damage and secondary malignancies after transplantation and are at high risk for psychological and cognitive consequences that require long-term follow-up care. This session will discuss the complications associated with pediatric transplantation and the importance of follow-up care for prevention and treatment of these complications when possible.

Learning Objectives:

  1. Identify complications in long-term survivors of pediatric BMT including relapse, infertility, organ damage, and secondary malignancies.
  2. Discuss management strategies for pediatric transplant survivors.
  3. Discuss the unique short- and long-term psychological and cognitive consequences of BMT in the pediatric population.

2:00 p.m.

Treatment and Management of Infectious Diseases and Graft-vs-Host Disease in BMT, Nandita Khera, MD, MPH, Mayo Clinic Arizona

Infection and graft-vs-host disease (GVHD) remain the major source of morbidity and mortality in patients who undergo BMT. New methods to improve treatment and decrease the complications and side effects of BMT are continually being explored. This session will discuss GVHD and the management of opportunistic infections among BMT recipients.

Learning Objectives:

  1. Review guidelines for preventing opportunistic infections among BMT recipients.
  2. Explain the pharmaceutical management of GVHD and posttransplant infections in BMT.
  3. Discuss GVHD management posttransplant.

2:45 p.m.



3:00 p.m.

The Impact of Health Care Reform on Transplantation, Alan Langnas, DO, University of Nebraska Medical Center

In the effort to reduce the cost of health care, an initiative was created to provide incentives for health care payors and providers to pursue quality improvement strategies together. The goal is to achieve efficiencies in the delivery of health care and guide patients to the most appropriate care. This session will discuss how health care reform will impact transplant patients and review patients’ and providers’ perspectives.

Learning Objectives:

  1. State key factors of the healthcare reform and how implementation will impact transplant patients.
  2. Review the Affordable Care Act (ACA) implementation and design that are impacting transplantation.

4:00 p.m.

Management of Psychosocial Issues in Transplant Recipients, Kim Phillips, MSN, RN,  CCTC, University of Utah Health Care

A key long-term goal for the transplant team is the promotion of patients' psychosocial well-being and quality of life and prevention of psychosocial and compliance-related behaviors. Therefore, maintaining regular contact and follow-up with patients is as important in the long term as it was before and during the first year after transplantation. Careful preliminary psychosocial assessment is essential to review candidates for factors that are predictive of relapse, while close follow up posttransplant can help improve outcomes. This session will review strategies for identifying high-risk patients and finding ways to intervene both pre- and post-transplantation to help lengthen transplant recipients' life spans, improve their adaptation to transplantation, and improve their quality of life.

Learning Objectives:

  1. Examine the key psychosocial issues facing the transplant patient.
  2. Discuss psychosocial risk factors that place transplant patients at higher risk for noncompliance and negative outcomes.
  3. Describe potential assessments and interventions that the transplant team might use to address psychosocial issues.

5:00 p.m.-7:00 p.m.

Complimentary Get-acquainted Reception
Join your colleagues for hors d'oeuvres and beverages. You won’t want to miss this opportunity to gather information and ideas from colleagues and exhibitors regarding the management of complex medical conditions.

TUESDAY, APRIL 14, 2015Up to 6.5 continuing education credits available.—ACPE UAN 0860-0000-15-027-L01-P

7:30 a.m.

Registration and Continental Breakfast

8:00 a.m.

Opening Remarks


8:15 a.m.

Multidisciplinary Management of End-Stage Renal Disease and Kidney and Pancreas Transplantation, Dixon B. Kaufman, MD, PhD, FACS, University of Wisconsin Hospital and Clinics

Diabetes is one of the leading causes of end-stage renal disease (ESRD) and the most frequent indication for kidney transplantation. Kidney and pancreas transplantation is an established definitive treatment for selected type 1 diabetic patients with end-stage diabetic nephropathy. A multidisciplinary team approach is paramount in the success of the transplant. This session will discuss the importance of a multidisciplinary team, patient selection, and the management of kidney and pancreas transplant patients pre- and post-transplant. Efforts to increase the number of available donor kidneys by facilitating additional donations of living donor kidneys will also be discussed.

Learning Objectives:

  1. Discuss patient selection, evaluation, posttransplant management, and complications of kidney and pancreas transplant.
  2. Describe the importance of a multidisciplinary approach for successful outcomes.
  3. Explain the significance of kidney paired donation and preemptive transplant in facilitating outcomes for kidney transplantation.

9:15 a.m.

Thoracic Transplantation: Heart and Lung, Greg Richardson, RN, CCTC, Barnes-Jewish Hospital

For many patients with end-stage heart failure who remain symptomatic despite optimal medical therapy, heart transplantation is the treatment of choice. Over the past decade, lung transplantation has become an increasingly important mode of therapy for patients with a variety of end-stage lung diseases. The ultimate decision to place a patient on the heart or lung transplant waiting list is made by clinicians at the transplant center based upon a combination of test data and clinical judgment. Candidates for heart and lung transplantation are generally younger persons with a fatal disease, and the transplant process offers hope. This session will discuss the advantages of a comprehensive multidisciplinary approach to managing thoracic transplant recipients. Indications and contraindications for transplant and how a team can work together to achieve optimal patient outcomes will be presented.

Learning Objectives:

  1. Outline the process of patient selection, evaluation, and long-term posttransplant management for heart and lung transplant patients.
  2. List the indications and contraindications for thoracic transplant.
  3. Discuss the importance of a multidisciplinary team approach to maximize patient outcomes.

10:15 a.m.


10:30 a.m.

Intestinal Rehabilitation and Transplantation, Cal S. Matsumoto, MD, MedStar Georgetown Transplant Institute

An intestinal transplant is a last-resort treatment option for patients with intestinal failure who develop life-threatening complications from total parenteral nutrition. Over the last 15 years, intestinal transplant outcomes have significantly improved and the number of transplants performed annually has steadily increased. Recent advances in small bowel transplantation and nontransplant surgical techniques now offer hope of sustained survival in the future without parenteral nutrition. This session will discuss the advantages of a comprehensive multidisciplinary approach to treating intestinal failure, indications for transplant, and how a team can work together to achieve optimal patient outcomes.

Learning Objectives:

  1. Define intestinal failure and identify potential causes.
  2. Discuss the long-term complications associated with intestinal failure.
  3. Recognize the indications for intestinal transplant.
  4. Describe the benefits of an intestinal-failure-program approach that combines the expertise of both rehabilitation and transplantation.

11:15 a.m.

Pharmaceuticals in Organ Transplantation, Rebecca L. Corey, PharmD, BCPS, and Jenise Stephen, PharmD, Mayo Clinic Arizona

Immunosuppression management post transplantation has evolved substantially. With ongoing clinical trials, acute rejection is typically easy to manage, and the current challenge is balancing the risk of rejection with the risk of drug toxicity. This session will address effective use of the most updated protocols for immunosuppression in solid organ transplantation.

Learning Objectives:

  1. Explain the mechanism of action of immunosuppressive agents along with the major adverse effects for each agent.
  2. Review the different classes of immunosuppressive medications used in transplantation.
  3. Discuss how immunosuppressive regimens may vary and identify best practices.
  4. State the importance of establishing an individualized immunosuppression regimen posttransplant.

12:00 p.m.

Luncheon Presentation: Ethics in Transplant, Giuliano Testa, MD, FACS, MBA, Baylor University Medical Center

A primary ethical dilemma surrounding organ transplantation arises from the shortage of available organs. Because of this shortage, patients may look for a living donor to donate an organ, allowing them to bypass the national waiting pool to receive a cadaveric organ. This session will discuss the ethical principle of coercion as it relates to living organ donor transplantation and will also address other ethical issues in solid organ transplantation.

Learning Objectives:

  1. Recognize and discuss the ethical principle of coercion as it relates to living organ donor transplantation.
  2. Identify and discuss two ethical issues related to solid organ transplantation.

1:00 p.m.

Dessert Break

1:15 p.m.

Posttransplant Complications in Solid Organ Transplants, Anil Seetharam, MD, Banner Health Good Samaritan Medical Center

After a patient receives a transplanted organ, several complications may occur including infection, malignancy, bone disease, and cardiovascular disease. This session will discuss the management of short- and long-term posttransplant complications.
Learning Objectives:

  1. Identify potential short- and long-term complications posttransplant including infection, malignancy, bone disease, and cardiovascular disease.
  2. Explain the medical and pharmacologic management of posttransplant complications.

2:00 p.m.

Heart Failure and Ventricular Assist Devices, Suzanne Chilcott, BSN, RN, Sharp Memorial Hospital

While the demand for heart transplantation has increased, the limited availability of hearts has remained constant. To bridge this gap, ventricular assist devices (VADs) are being used to enable patients to survive until a heart becomes available, or in some cases, to extend the lives of patients who do not qualify for a heart transplant. Managing patients on chronic VAD support requires regular patient follow-up and multidisciplinary care teams. This presentation will review management strategies to reduce morbidity and mortality in heart failure patients supported chronically with VADs and describe candidate selection, outpatient strategies to optimize device performance, complications that warrant close monitoring, heart failure management, and currently available devices.

Learning Objectives:

  1. Review management strategies to reduce morbidity and mortality in heart failure patients supported chronically with VADs.
  2. Describe candidate selection, outpatient strategies to optimize device performance, and complications that warrant close monitoring.
  3. Provide an overview of the VADs currently available.

2:45 p.m.

Liver Transplant: Patient Selection, Indications, and Optimizing Outcomes, R. Mark Ghobrial, MD, PhD, FACS, FRCS (Ed), Methodist J.C. Walter Jr. Transplant Center

Liver transplantation is a treatment option for patients with acute liver failure, end-stage liver disease, and primary hepatic malignancy. Specialists from a variety of fields are needed to assess if a liver transplant is appropriate and often a team of such specialists are assembled to evaluate and determine candidates for a liver transplant. The decision to list a patient for transplantation is based on a number of factors including the inherent risks of surgery, recurrent disease, and long-term immunosuppression—all of which are weighed against the potential benefits of transplantation. This session will discuss diseases that are treated with liver transplantation, the process of patient selection, evaluation, and surgical techniques used in liver transplant, along with the importance of a multidisciplinary team for optimal outcomes.

Learning Objectives:

  1. Outline the process of patient selection, evaluation, and surgical techniques used in liver transplantation.
  2. List diseases that are treatable with liver transplantation.
  3. Discuss the importance of a multidisciplinary team approach for optimal transplant outcomes.

3:30 p.m.


Note: OptumHealth Education reserves the right to make any necessary changes to this program. Efforts will be made to keep presentations as scheduled. However, unforeseen circumstances may result in the substitution of faculty or content.
Last updated: 3/12/15