This educational activity consists of recorded presentations from Innovations in Solid Organ and Blood/Marrow Transplantation held in Scottsdale, Arizona on March 7-9, 2011.
Split-liver transplantation has now become an acceptable treatment option for both adult and pediatric recipients with end-stage-liver disease. The introduction of reduced-liver transplant, in which a portion of the adult liver is given to infants and children, dramatically reduced the recipients’ mortality rate. Over the past 20 years, the risk of death among patients on the pediatric wait list has substantially declined because of the ability to use these reduced-size grafts and because of the subsequent introduction of live-donor transplantation. This presentation will review the history and evolution of split-liver transplantation, as well as discuss its impact on the pediatric waiting list.

Learning Objectives
At the end of this educational activity, participants should be able to

1. Review the history and evolution of split-liver transplantation.
2. Discuss the impact of split-liver transplantation on the pediatric waiting list.
3. Analyze the possible barriers to effective implementation of split-liver transplantation.

Faculty
Riccardo A. Superina, MD
Robert E. Schneider Chair in Surgery
Feinberg School of Medicine;
Northwestern University
Division Chief, Transplant Surgery
Co-Director, Siragusa Transplantation Center
Children's Memorial Hospital
Chicago, Illinois

Disclosures
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Method of Participation
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Participants will receive a certificate upon successful completion of the activity, which includes the following:

• Completing the entire activity
• Completing the Pre- and Post-Activity Assessments, Activity Evaluation, and Application for Certificate of Credit forms

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Sponsored By
This activity is sponsored by OptumHealth Education.

Commercial Support
This activity is supported by Allos Therapeutics, Amgen, Novartis Oncology, Shire, Cephalon Oncology, genzyme, Millennium, Novartis, sanofi aventis, National Marrow Donor Program, and The Children's Hospital of Philadelphia.

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